RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-22
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
qRT-PCR; cell counting kit-8 analysis etc.
Target
PTAFR
Pathway
NA
PubMed ID
Title
MiR-30b-5p and miR-22-3p restrain the fibrogenesis of post-myocardial infarction in mice via targeting PTAFR
Year
2020
Function
"miR-30b-5p and miR-22-3p exerted the suppression of fibrogenesis in ang ii-treated cardiac fibroblasts (CFs) via targeting PTAFR, insinuating the indicative roles of miR-30b-5p and miR-22-3p in the fibrogenesis process."